 | | | |   Lymphocyte Function-Associated Antigen-1 |
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TE.188653 | |  Lymphocyte Function-Associated Antigen-1
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définition  | - An integrin heterodimer widely expressed on cells of hematopoietic origin. CD11A ANTIGEN comprises the alpha chain and the CD18 antigen (ANTIGENS, CD18) the beta chain. Lymphocyte function-associated antigen-1 is a major receptor of T-CELLS; B-CELLS; and GRANULOCYTES. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by NATURAL KILLER CELLS and granulocytes. Intracellular adhesion molecule-1 has been defined as a ligand for lymphocyte function-associated antigen-1.
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termes  | |
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termes | - Lymphocyte Function-Associated Antigen-1
- Integrin alphaLbeta2
- Leukocyte Function Associated Antigen-1
- LFA-1
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